Has anyone used a parasite’s genome map to design a genetic control or poison to eradicate the parasite.?

African trypanosomiasis. Commonly called sleeping sickness, this disease is caused by a parasitic microbe transmitted by tsetse flies. If untreated, the parasite migrates to the central nervous system, causing seizures, mental disorders and, ultimately, death. As many as 70,000 people are infected in Central and East Africa.

American trypanosomiasis. Commonly called Chagas disease, this disease is caused by a parasitic microbe transmitted by blood-sucking bugs. It can cause organ damage. The parasite infects about 13 million people, mostly in Latin America.

Hookworm. Human hookworm infection is caused by intestinal worm parasites transmitted to humans from contaminated soil. It causes internal blood loss and is the world’s leading cause of anemia and protein malnutrition, particularly in pregnant women and children. More than half a billion people in poverty-stricken areas of Africa, Latin America, Southeast Asia and China are infected.

Leishmaniasis. This disease is caused by a parasitic microbe transmitted by sand flies. It can cause skin lesions and swelling of the spleen and liver. More than 12 million people are infected in Africa, Asia, Europe and the Americas.

Lymphatic filariasis. Commonly called elephantiasis, this parasitic worm disease is spread by mosquitoes. It can lead to disabling swelling of the legs and other body parts. About 120 million people are infected throughout Asia, Africa, the Western Pacific, South America and parts of the Caribbean.

Malaria. This disease is caused by a parasitic microbe spread by mosquitoes. Each year, malaria infects at least 300 million people living in tropical regions. It can cause brain damage or death if red blood cells infected with malaria parasites build up in the brain’s blood vessels. The annual death toll is about 1 million people, many of whom are children under age 5 and pregnant women.

Onchocerciasis. Commonly called river blindness, this parasitic worm disease is spread by black flies. It can cause extreme itching, sores on the skin and blindness. The parasite infects about 18 million people, mostly in Africa, but also in Latin America.

Schistosomiasis. Also known as bilharzia or snail fever, this parasitic worm disease is transmitted by snails that live in fresh water. It can impair growth, cause severe anemia and lead to kidney and liver malfunctions. More than 200 million people are infected, mostly in Africa and Asia.
A respectable number of parasite genomes have been mapped.

http://www.genomenewsnetwork.org/resources/sequenced_genomes/genome_guide_p1.shtml

Has anyone yet succeeded in designing a control to from knowledge of the parasite genome?

As far as Schistosomiasis, it was just completed over the summer. Hopefully drugs to follow. see more here: http://bactiman63.blogspot.com/2009/07/genetic-code-to-schistosomes-complete.html